Left Atrial Epithelioid Angiosarcoma Presenting As Recurrent Stroke: A Case Report

A 74-year-old man presented with recurrent cerebellar infarction and progressive anemia. The workup revealed a small jejunal tumor and a mobile mass in the left atrium. Urgent minimally invasive cardiac surgery was performed, and histopathology confirmed epithelioid angiosarcoma. Subsequent small bowel resection revealed a similar tumor. Despite chemotherapy and radiotherapy, bone metastases progressed, and the patient succumbed to the disease eight months postoperatively. The cardiac tumor was smaller than typically reported, suggesting early detection prompted by embolic events. Nevertheless, the clinical course was aggressive, highlighting the high malignancy of epithelioid angiosarcoma and the limited effectiveness of current therapies. Accumulation of further clinical experience is essential to improve outcomes in this rare cardiac tumor.

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Publication Details

Journal
Cureus
Published
2025-11-09
DOI
https://doi.org/10.7759/cureus.96455
Primary Topic
Cardiac tumors and thrombi
Type
article
Field-Weighted Citation Impact
0.00
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article

Left Atrial Epithelioid Angiosarcoma Presenting As Recurrent Stroke: A Case Report

Masaomi Fukuzumi, Tadashi Kitamura, Yusuke Motoji, Kagami Miyaji et al.
Cureus
Cardiac tumors and thrombi
article

Left Atrial Epithelioid Angiosarcoma Presenting As Recurrent Stroke: A Case Report

Masaomi Fukuzumi, Tadashi Kitamura, Yusuke Motoji, Kagami Miyaji, Yoshimi Tamura
article en

Abstract

A 74-year-old man presented with recurrent cerebellar infarction and progressive anemia. The workup revealed a small jejunal tumor and a mobile mass in the left atrium. Urgent minimally invasive cardiac surgery was performed, and histopathology confirmed epithelioid angiosarcoma. Subsequent small bowel resection revealed a similar tumor. Despite chemotherapy and radiotherapy, bone metastases progressed, and the patient succumbed to the disease eight months postoperatively. The cardiac tumor was smaller than typically reported, suggesting early detection prompted by embolic events. Nevertheless, the clinical course was aggressive, highlighting the high malignancy of epithelioid angiosarcoma and the limited effectiveness of current therapies. Accumulation of further clinical experience is essential to improve outcomes in this rare cardiac tumor.

CureusVol. 17(11)
Jichi Medical University (JP), National Center for Global Health and Medicine (JP), Center for Global Health (US), Kitasato University (JP)
Openalex Percentile: Top 49%
Cardiac tumors and thrombi
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