Decoding IL-1 receptor 1 and 2 expression profiles across organs in sepsis
We reveal distinct and compartmentalized expression landscapes for IL-1R1 and IL-1R2 across organs during sepsis. These findings offer a deep understanding of IL-1 receptors biology and shed light on their contributions to immune modulation and tissue-specific responses in sepsis.
Authors
- Han Ma (ORCID: https://orcid.org/0000-0003-0846-470X)
- Weiqin Wang (ORCID: https://orcid.org/0000-0002-2259-7835)
- Yue Peng (ORCID: https://orcid.org/0009-0006-1193-6324)
- Huali Zhang (ORCID: https://orcid.org/0000-0002-0788-7092)
- Chuyi Tan (ORCID: https://orcid.org/0000-0001-6364-6288)
- Huan Chen (ORCID: https://orcid.org/0000-0001-7906-7635)
- Yiying Yang (ORCID: https://orcid.org/0000-0001-7755-7956)
Institutions
- Central South University (CN)
- Third Xiangya Hospital (CN)
Publication Details
- Journal
- Frontiers in Cell and Developmental Biology
- Published
- 2025-11-10
- DOI
- https://doi.org/10.3389/fcell.2025.1675870
- Citations
- 1
- Primary Topic
- Immune Response and Inflammation
- Type
- article
- Field-Weighted Citation Impact
- 0.80
Funders
- National Natural Science Foundation of China
- China Postdoctoral Science Foundation