In Vitro biomechanical study of meniscal properties in patients with severe knee osteoarthritis
The biomechanical properties of the meniscus in severe KOA patients differ substantially from those reported in healthy tissues, highlighting the need for caution when using literature-derived parameters in computational modeling. The iFEA framework provides a robust approach for predicting constitutive parameters across different degeneration levels and meniscal regions, offering valuable insights for personalized knee joint modeling and simulation.
Authors
- Songhua Yan (ORCID: https://orcid.org/0000-0001-6764-1679)
- Jizhou Zeng
- Haixia Zhang (ORCID: https://orcid.org/0000-0001-5489-5987)
- Yuqi Liu (ORCID: https://orcid.org/0000-0001-5792-5723)
- Kuan Zhang (ORCID: https://orcid.org/0000-0003-4195-1198)
Institutions
- Capital Medical University (CN)
- Beijing Luhe Hospital Affiliated to Capital Medical University (CN)
Publication Details
- Journal
- Frontiers in Bioengineering and Biotechnology
- Published
- 2025-11-10
- DOI
- https://doi.org/10.3389/fbioe.2025.1637649
- Citations
- 1
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 1.67
Funders
- National Natural Science Foundation of China
- Capital Medical University