Is neoadjuvant chemoradiotherapy necessary for locally advanced rectal cancer above the anterior peritoneal reflection?

It was feasible to accurately identify APR using MRI and distinguish upper and lower rectal cancer. CRT might not be essential for LARC patients above the APR after excluding T4b cases, which can avoid unnecessary treatment.

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Publication Details

Journal
Future Oncology
Published
2025-11-10
DOI
https://doi.org/10.1080/14796694.2025.2582211
Primary Topic
Colorectal Cancer Surgical Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Is neoadjuvant chemoradiotherapy necessary for locally advanced rectal cancer above the anterior peritoneal reflection?

Huashan Liu, Fujin Ye, Minyi He, Pinzhu Huang et al.
Future Oncology
Colorectal Cancer Surgical Treatments
article

Is neoadjuvant chemoradiotherapy necessary for locally advanced rectal cancer above the anterior peritoneal reflection?

Huashan Liu, Fujin Ye, Minyi He, Pinzhu Huang, Mian Chen, Qiulan He, Liang Huang, Liang Kang, Xiaobin Zheng, Shuangling Luo, Wuteng Cao, Taixuan Wan
article en

Abstract

It was feasible to accurately identify APR using MRI and distinguish upper and lower rectal cancer. CRT might not be essential for LARC patients above the APR after excluding T4b cases, which can avoid unnecessary treatment.

Future OncologyVol. 21(28)
Sun Yat-sen University (CN), Sixth Affiliated Hospital of Sun Yat-sen University (CN), The First Affiliated Hospital, Sun Yat-sen University (CN)
Openalex Percentile: Top 54%
Colorectal Cancer Surgical Treatments
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Is neoadjuvant chemoradiotherapy necessary for locally advanced rectal cancer above the anterior peritoneal reflection? — Huashan Liu, Fujin Ye, et al. · Future Oncology (2025) | TGRS Research Map | TGRS