Pulmonary Vascular Endothelial Dysfunction Is Induced by Nonpulsatile Pulmonary Blood Flow in an Ovine Classic Glenn Model
The initiation of nonpulsatile PBF following the Glenn induces early EC dysfunction independent of hypoxemia and polycythemia.
Authors
- Gail H. Deutsch (ORCID: https://orcid.org/0000-0002-0571-0285)
- Stephen M. Black (ORCID: https://orcid.org/0000-0002-4524-6544)
- Jason Boehme (ORCID: https://orcid.org/0000-0003-4908-9934)
- Michael A. Smith (ORCID: https://orcid.org/0000-0002-7899-7248)
- Jeffrey R. Fineman (ORCID: https://orcid.org/0000-0001-9740-405X)
- Gary W. Raff (ORCID: https://orcid.org/0000-0001-8118-630X)
- Emin Maltepe (ORCID: https://orcid.org/0000-0002-1271-7565)
- Sanjeev A. Datar (ORCID: https://orcid.org/0009-0003-6986-2821)
- John Hwang (ORCID: https://orcid.org/0000-0002-7350-407X)
- Jonathan Hyde (ORCID: https://orcid.org/0000-0002-0699-7281)
- Ting Wang (ORCID: https://orcid.org/0000-0001-6446-4056)
- Wenhui Gong
- Eric G. Johnson (ORCID: https://orcid.org/0000-0002-3059-4052)
- Naveen Swami
- Y S Chao
- Carina Nilsson
Institutions
- University of California, San Francisco (US)
- Florida International University (US)
- University of Washington (US)
- Copenhagen University Hospital (DK)
- Vaccine & Gene Therapy Institute of Florida (US)
- University of San Francisco (US)
- University of California, Davis (US)
Publication Details
- Journal
- Comprehensive physiology
- Published
- 2025-11-10
- DOI
- https://doi.org/10.1002/cph4.70071
- Primary Topic
- Nitric Oxide and Endothelin Effects
- Type
- article
- Field-Weighted Citation Impact
- 0.00