Effects of noradrenaline, vasopressin, phenylephrine or metaraminol on kidney and brain microcirculation in ovine cardiopulmonary bypass: a randomised trial
Intra-operative noradrenaline during ovine cardiopulmonary bypass worsens renal medullary tissue oxygenation relative to vasopressin. These findings suggest that the choice of vasopressors may affect renal oxygenation.
Authors
- Jai Raman (ORCID: https://orcid.org/0000-0002-7691-4779)
- Rinaldo Bellomo (ORCID: https://orcid.org/0000-0002-1650-8939)
- Roger G. Evans (ORCID: https://orcid.org/0000-0002-9241-0757)
- Yugeesh R. Lankadeva (ORCID: https://orcid.org/0000-0002-3589-9111)
- Abraham H. Hulst (ORCID: https://orcid.org/0000-0001-9101-7649)
- Clive Newton May (ORCID: https://orcid.org/0000-0001-8548-3846)
- Lachlan Fraser Miles (ORCID: https://orcid.org/0000-0003-2044-5560)
- Anton Lewis Trask-Marino (ORCID: https://orcid.org/0000-0003-4058-8905)
- Peter McCall (ORCID: https://orcid.org/0000-0003-1209-6882)
- Alemayehu Hailu Jufar (ORCID: https://orcid.org/0009-0000-2669-7836)
- Taku Furukawa (ORCID: https://orcid.org/0000-0001-9898-5802)
- Andrew Donald Cochrane (ORCID: https://orcid.org/0000-0002-2036-013X)
- Bruno Marino (ORCID: https://orcid.org/0000-0002-7392-1615)
- Sally G. Hood
Institutions
- The University of Melbourne (AU)
- Florey Institute of Neuroscience and Mental Health (AU)
- Discovery Institute (US)
- Australian Regenerative Medicine Institute (AU)
- Australian and New Zealand Intensive Care Society (AU)
- Amsterdam Neuroscience (NL)
- Austin Health (AU)
- Amsterdam University of Applied Sciences (NL)
- Monash University (AU)
- Victoria University (AU)
- University of Amsterdam (NL)
Publication Details
- Journal
- Anaesthesia
- Published
- 2025-11-10
- DOI
- https://doi.org/10.1111/anae.70049
- Citations
- 1
- Primary Topic
- Acute Kidney Injury Research
- Type
- article
- Field-Weighted Citation Impact
- 1.43