Feasibility of the pre‐operative measurement of fractional exhaled nitric oxide and respiratory mechanics to predict respiratory outcomes in children undergoing general anaesthesia
We have shown the feasibility of study enrolment and pre-operative fractional exhaled nitric oxide measurement but had difficulty obtaining measurements of respiratory mechanics (forced oscillation technique). Neither test improved the prediction of peri-operative respiratory adverse events reliably in this group of patients. A thorough pre-operative clinical history combined with care by an experienced paediatric anaesthetist remains the most reliable means of reducing peri-operative respiratory adverse events.
Authors
- Neil Hauser (ORCID: https://orcid.org/0000-0002-8868-0690)
- Julie Nguyen (ORCID: https://orcid.org/0000-0003-3300-7033)
- R. Nazim Khan (ORCID: https://orcid.org/0000-0003-3349-5006)
- Britta Sylvia von Ungern-Sternberg (ORCID: https://orcid.org/0000-0002-8043-8541)
- Daisy Evans (ORCID: https://orcid.org/0000-0001-8262-5706)
- Aine Sommerfield (ORCID: https://orcid.org/0000-0001-8418-5572)
- Chris O'Dea
- David Sommerfield (ORCID: https://orcid.org/0000-0003-3600-1315)
Institutions
- The Kids Research Institute Australia (AU)
- The University of Western Australia (AU)
- Princess Margaret Hospital for Children (AU)
- Institute for Respiratory Health (AU)
- Perth Children's Hospital
Publication Details
- Journal
- Anaesthesia
- Published
- 2025-11-10
- DOI
- https://doi.org/10.1111/anae.70056
- Primary Topic
- Respiratory Support and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00