Targeting Progesterone Receptor Membrane Component 1 to Improve Muscle Development and Glucose Homeostasis

These findings identify skeletal muscle PGRMC1 as a pivotal regulator of glucose metabolism and highlight its inhibition as a promising muscle-targeted therapeutic approach for T2D management.

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Publication Details

Journal
Journal of Cachexia Sarcopenia and Muscle
Published
2025-11-10
DOI
https://doi.org/10.1002/jcsm.70121
Primary Topic
Metabolism, Diabetes, and Cancer
Type
article
Field-Weighted Citation Impact
0.00

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article

Targeting Progesterone Receptor Membrane Component 1 to Improve Muscle Development and Glucose Homeostasis

In‐Jeoung Baek, Young Hoon Sung, Moeka Mukae, Globinna Kim et al.
Journal of Cachexia Sarcopenia and Muscle
Metabolism, Diabetes, and Cancer
article

Targeting Progesterone Receptor Membrane Component 1 to Improve Muscle Development and Glucose Homeostasis

In‐Jeoung Baek, Young Hoon Sung, Moeka Mukae, Globinna Kim, Eui‐Ju Hong, Tae‐Won Kim, Sang R. Lee, Jungeun Park, Young Suk Won, Hyo‐Jung Kwun
article en

Abstract

These findings identify skeletal muscle PGRMC1 as a pivotal regulator of glucose metabolism and highlight its inhibition as a promising muscle-targeted therapeutic approach for T2D management.

Journal of Cachexia Sarcopenia and MuscleVol. 16(6)
Chungnam National University (KR), University of Ulsan (KR), Dong-A University (KR), Korea Research Institute of Bioscience and Biotechnology (KR)
National Research Foundation, National Research Foundation of Korea, Ministry of Science and ICT, South Korea
Openalex Percentile: Top 70%
Metabolism, Diabetes, and Cancer
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Targeting Progesterone Receptor Membrane Component 1 to Improve Muscle Development and Glucose Homeostasis — In‐Jeoung Baek, Young Hoon Sung, et al. · Journal of Cachexia Sarcopenia and Muscle (2025) | TGRS Research Map | TGRS