Diagnostic Stewardship Trends and Antimicrobial Resistance Profiles of Bacteria Isolated in Zambia: A Five-Year Retrospective Study (2020–2024)
Zambia faces a concerning and significant increase in AMR, with high resistance prevalence across commonly used antibiotics. Critical resistance alerts for VRE, linezolid, carbapenems, and possible ESBL-producing <i>Enterobacterales</i> underscore an urgent need for robust antimicrobial stewardship and continuous diagnostic surveillance.
Authors
- Kaunda Yamba (ORCID: https://orcid.org/0000-0003-1777-8305)
- Kelvin Mwangilwa (ORCID: https://orcid.org/0000-0002-5099-3392)
- Bertha Chibwe
- Steward Mudenda (ORCID: https://orcid.org/0000-0003-1692-8981)
- Chie Nakajima (ORCID: https://orcid.org/0000-0002-9194-1062)
- Victor Daka (ORCID: https://orcid.org/0000-0001-9490-5609)
- Duncan Chanda (ORCID: https://orcid.org/0000-0001-5477-9054)
- Fusya Goma
- Nyambe Sinyange
- Herman M. Chambaro (ORCID: https://orcid.org/0000-0003-1407-6818)
- Amon Siame
- Webrod Mufwambi (ORCID: https://orcid.org/0000-0003-1952-1423)
- Aubrey Chichonyi Kalungia (ORCID: https://orcid.org/0000-0003-2554-1236)
- Chileshe Lukwesa
- Kaunda Kaunda
- John Bwalya Muma (ORCID: https://orcid.org/0000-0001-6180-4051)
- Ruth Nakazwe
- Joseph Yamweka Chizimu (ORCID: https://orcid.org/0000-0002-2126-5759)
- Zoran Muhimba
- Jimmy Mapenzi Hangoma (ORCID: https://orcid.org/0000-0001-8973-9474)
- Maisa Kasanga (ORCID: https://orcid.org/0000-0003-1724-7934)
- Doreen Mainza Shempela (ORCID: https://orcid.org/0009-0003-4945-6746)
- Priscilla Nkonde Gardner (ORCID: https://orcid.org/0000-0001-8937-3142)
- Andrew Bambala (ORCID: https://orcid.org/0000-0003-1074-4356)
- Geoffrey Mainda (ORCID: https://orcid.org/0000-0001-8139-6737)
- Roma Chilengi (ORCID: https://orcid.org/0000-0003-0221-9527)
- Freddie Masaninga (ORCID: https://orcid.org/0000-0002-4040-1736)
- Ntombi B. Mudenda (ORCID: https://orcid.org/0009-0000-4013-7843)
- O-Tipo Shikanga
- Yasuhiko Suzuki (ORCID: https://orcid.org/0000-0002-1313-1494)
- Misheck Shawa
- Mwendalubi Albert Hadunka (ORCID: https://orcid.org/0009-0001-6480-6885)
- Chikwanda Chileshe
- Taona Sinyawa
- Samson Mukale
- Malambo Mutila (ORCID: https://orcid.org/0000-0002-4148-1993)
- Mpela Chibi
- Fred Mulako Simwinji
- Sandra Diana Mwadetsa (ORCID: https://orcid.org/0009-0008-0221-4260)
- Loveness Sakalimbwe
Institutions
- Hokkaido University of Science (JP)
- Centre for Infectious Disease Research in Zambia (ZM)
- Food and Agriculture Organization of the United Nations (IT)
- Hokkaido University (JP)
- University Teaching Hospital (ZM)
- Lusaka Apex Medical University (ZM)
- Copperbelt University (ZM)
- University of Zambia (ZM)
- Zambia National Public Health Institute (ZM)
- Ministry of Agriculture and Livestock (ZM)
- National HIV/AIDS/STI/TB Council (ZM)
- World Health Organization - Zambia (ZM)
- University of Africa (ZM)
- National Institute of Public Administration (ZM)
Publication Details
- Journal
- Antibiotics
- Published
- 2025-11-10
- DOI
- https://doi.org/10.3390/antibiotics14111136
- Citations
- 1
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.59
Funders
- World Health Organization
- Japan Agency for Medical Research and Development