Effects of <scp>SGLT2</scp> inhibitors across the spectrum of albuminuria in cardiovascular–kidney–metabolic conditions: A pooled analysis of randomised trials
Higher albuminuria was associated with an increased risk of cardiovascular and kidney outcomes. SGLT2i improved cardiovascular and kidney outcomes across the full range of albuminuria, including normo-albuminuria.
Authors
- Stefan D. Anker (ORCID: https://orcid.org/0000-0002-0805-8683)
- Abhinav Sharma (ORCID: https://orcid.org/0000-0002-2346-8330)
- Javed Butler (ORCID: https://orcid.org/0000-0001-7683-4720)
- Gerasimos S Filippatos (ORCID: https://orcid.org/0000-0002-5640-0332)
- Milton Packer (ORCID: https://orcid.org/0000-0003-1828-2387)
- João Sérgio Neves (ORCID: https://orcid.org/0000-0002-8173-8255)
- Pedro Marques (ORCID: https://orcid.org/0000-0003-1132-3983)
- Francisco Vasques‐Nóvoa (ORCID: https://orcid.org/0000-0001-9701-8538)
- Luís Mendonça (ORCID: https://orcid.org/0000-0003-1951-3941)
- João Pedro Ferreira (ORCID: https://orcid.org/0000-0002-2304-6138)
- Faiez Zannad
Institutions
- Inserm (FR)
- Universidade do Porto (PT)
- National and Kapodistrian University of Athens (GR)
- McGill University Health Centre (CA)
- Baylor University Medical Center (US)
- Hospital de São João (PT)
- University of Mississippi (US)
- Administração Regional de Saúde de Lisboa e Vale do Tejo (PT)
- German Centre for Cardiovascular Research (DE)
- Baylor Scott & White Health (US)
- French Clinical Research Infrastructure Network (FR)
- Imperial College London (GB)
- Charité - Universitätsmedizin Berlin (DE)
Publication Details
- Journal
- Diabetes Obesity and Metabolism
- Published
- 2025-11-10
- DOI
- https://doi.org/10.1111/dom.70289
- Citations
- 1
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 1.29
Funders
- Eli Lilly and Company
- Yale University
- McGill University
- Raymond and Beverly Sackler Institute for Biological, Physical and Engineering Sciences, Yale University
- Canadian Institutes of Health Research
- Fundação para a Ciência e a Tecnologia
- Janssen Research and Development