Hereditary combined deficiency of vitamin K–dependent clotting factors presenting as postoperative haemorrhage in a Syrian adolescent: a likely VKCFD type 2 phenotype

Consider vitamin K-dependent clotting factors deficiency in unexplained prolonged prothrombin time/activated partial thromboplastin time with normal vitamin K and combined factor deficiencies.Early recognition prevents catastrophic bleeding; vitamin K and factor replacement are lifesaving.Internists play a pivotal role in differentiating inherited from acquired coagulopathies.

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Publication Details

Journal
European Journal of Case Reports in Internal Medicine
Published
2025-11-10
DOI
https://doi.org/10.12890/2025_005928
Primary Topic
Vitamin K Research Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Hereditary combined deficiency of vitamin K–dependent clotting factors presenting as postoperative haemorrhage in a Syrian adolescent: a likely VKCFD type 2 phenotype

Mahmoud Alhamadeh Alswij, Anas Alyousef, Mais Musleh, Nighat Mir Ahmad et al.
European Journal of Case Reports in Internal Medicine
Vitamin K Research Studies
article

Hereditary combined deficiency of vitamin K–dependent clotting factors presenting as postoperative haemorrhage in a Syrian adolescent: a likely VKCFD type 2 phenotype

Mahmoud Alhamadeh Alswij, Anas Alyousef, Mais Musleh, Nighat Mir Ahmad, Abdullatif AlStem, Hadi Ataya
article en

Abstract

Consider vitamin K-dependent clotting factors deficiency in unexplained prolonged prothrombin time/activated partial thromboplastin time with normal vitamin K and combined factor deficiencies.Early recognition prevents catastrophic bleeding; vitamin K and factor replacement are lifesaving.Internists play a pivotal role in differentiating inherited from acquired coagulopathies.

European Journal of Case Reports in Internal MedicineVol. 12(12)
Damascus Hospital (SY), Al Wataniya Private University (SY), Al Assad University Hospital (SY), Damascus University (SY)
Openalex Percentile: Top 59%
Vitamin K Research Studies
DOIOpen Access PDFOpenAlex
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