Selenomethionine alleviates aortic dissection via PGC-1α/NRF2/TFAM-mediated mitochondrial biosynthesis against ferroptosis: an experimental study
Set alleviated AD progression by suppressing ferroptosis-mediated phenotypic switching of VSMCs through targeted activation of the PGC-1α/NRF2/TFAM axis.
Authors
- Shengwei Lai
- Yiming Bi (ORCID: https://orcid.org/0000-0002-0436-5301)
- Xinhao Wang (ORCID: https://orcid.org/0000-0003-4485-8343)
- Wei Guo (ORCID: https://orcid.org/0000-0002-8865-402X)
- Shuaifei Ji
- Zhiwei Lai (ORCID: https://orcid.org/0009-0007-2476-9622)
- Huang Qin (ORCID: https://orcid.org/0009-0005-2471-6075)
Institutions
- Tianjin University of Science and Technology (CN)
- Tianjin University of Technology (CN)
- Chinese PLA General Hospital (CN)
- Burn Institute (US)
- PLA Academy of Military Science (CN)
Publication Details
- Journal
- International Journal of Surgery
- Published
- 2025-11-10
- DOI
- https://doi.org/10.1097/js9.0000000000003561
- Citations
- 1
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 1.52