Diagnostic and Prognostic Value of cfDNA Concentration and Fragmentation in Prostate Cancer
The assay and analysis of plasma and urinary cfDNA fragmentation may provide useful biomarkers for PCa diagnosis and follow-up, particularly when differentiating between localized and metastatic disease. These findings are promising, but further research is required to determine their potential utility in clinical risk stratification and treatment monitoring.
Authors
- C. Martínez-Sanchiz
- J.M. Giménez Bachs (ORCID: https://orcid.org/0000-0003-2549-8813)
- Óscar Legido‐Gómez (ORCID: https://orcid.org/0000-0003-2988-7509)
- Sonsoles Navarro‐Jiménez
- A.S. Salinas Sánchez (ORCID: https://orcid.org/0000-0003-1837-6981)
- M.V. Lorenzo-Sánchez
- María G. Picazo-Martínez
- María J. Donate‐Moreno
- M.A. Tárraga-Honrubia
Institutions
- Hospital de Hellín (ES)
- Hospital General Universitario de Albacete (ES)
- Complejo Hospitalario Universitario de Albacete (ES)
- University of Castilla-La Mancha (ES)
Publication Details
- Journal
- The Prostate
- Published
- 2025-11-10
- DOI
- https://doi.org/10.1002/pros.70090
- Primary Topic
- Cancer Genomics and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Asociación Española de Urología