Evaluation of intraductal carcinoma and invasive cribriform carcinoma as predictors of genetic mutations in systemic treatment-naïve prostate cancer patients
The presence of intraductal carcinoma or cribriform growth patterns was not associated with increased likelihood of mutations in homologous recombination repair genes. These findings support the use of clinical parameters such as age and Grade Group, rather than histologic subtype alone, in guiding decisions for genetic testing.
Authors
- Jungyo Suh (ORCID: https://orcid.org/0000-0002-3867-4778)
- Bumjin Lim (ORCID: https://orcid.org/0000-0002-1746-6072)
- Inkeun Park (ORCID: https://orcid.org/0000-0003-3064-7895)
- Jun Hyuk Hong (ORCID: https://orcid.org/0000-0003-2705-0481)
- Jung Kwon Kim (ORCID: https://orcid.org/0000-0002-8069-6225)
- Dalsan You (ORCID: https://orcid.org/0009-0000-0408-4254)
- Hanjong Ahn (ORCID: https://orcid.org/0000-0001-7608-5352)
- Bokyung Ahn (ORCID: https://orcid.org/0000-0002-0229-2276)
- Sangmin Lee (ORCID: https://orcid.org/0000-0002-3457-0816)
- In Gab Jeong
Institutions
- Ulsan College (KR)
- Asan Medical Center (KR)
- University of Ulsan (KR)
- Kangwon National University Hospital (KR)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-11-10
- DOI
- https://doi.org/10.1186/s12885-025-15001-2
- Primary Topic
- Prostate Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Research Foundation
- National Research Foundation of Korea
- Asan Institute for Life Sciences, Asan Medical Center
- Ministry of Science and ICT, South Korea