Macrophage Activation-Like Syndrome in critically ill patients with sepsis: high risk patients with high mortality
MALS increased in-hospital mortality in sepsis patients. Our results underscore the urgent need for targeted research and therapeutic strategies. While promising insights into immune modulation have emerged, further studies are essential to refine treatment approaches and improve outcomes in this vulnerable patient population.
Authors
- Peter Nyvlt
- Claudia Spies (ORCID: https://orcid.org/0000-0002-1062-0495)
- Patrick Heeren (ORCID: https://orcid.org/0000-0001-9356-2296)
- Gunnar Lachmann (ORCID: https://orcid.org/0000-0003-2330-9839)
- Mirja Mittermaier (ORCID: https://orcid.org/0000-0003-0678-6676)
- Jana Ihlow (ORCID: https://orcid.org/0000-0001-5484-1321)
- Gritta Janka (ORCID: https://orcid.org/0000-0002-5397-3047)
- Frank M. Brunkhorst (ORCID: https://orcid.org/0000-0002-8132-8651)
- Paul La Rosée (ORCID: https://orcid.org/0000-0002-6758-7809)
- Friederike S. Schuster (ORCID: https://orcid.org/0000-0001-5447-7929)
- Clarissa von Haefen (ORCID: https://orcid.org/0000-0001-5740-1794)
- Thomas Schenk
- Cornelia Lachmann
Institutions
- Universität Hamburg (DE)
- Humboldt-Universität zu Berlin (DE)
- University Medical Center Hamburg-Eppendorf (DE)
- Jena University Hospital (DE)
- Schwarzwald-Baar Klinikum (DE)
- Berlin Institute of Health at Charité - Universitätsmedizin Berlin (DE)
Publication Details
- Journal
- Anaesthesia Critical Care & Pain Medicine
- Published
- 2025-11-11
- DOI
- https://doi.org/10.1016/j.accpm.2025.101678
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00