EGFR pathway alterations correlate with rapid early progression in glioblastoma
This study identifies EGFR alterations as a significant predictor of REP in glioblastoma. Patients with these alterations identified post-operatively may benefit from expedited adjuvant therapy to mitigate early tumor progression. Further research is needed to refine treatment strategies for this high-risk subset.
Authors
- Kaylie Cullison (ORCID: https://orcid.org/0000-0001-5341-1530)
- Aren Singh Saini (ORCID: https://orcid.org/0000-0002-6163-3288)
- Eric A. Mellon (ORCID: https://orcid.org/0000-0001-9892-8402)
- Janette Herr
- Kayla Samimi
Institutions
- University of Miami (US)
- Henry Ford Health System (US)
- Henry Ford Hospital (US)
- Sylvester Comprehensive Cancer Center (US)
- Michigan State University (US)
Publication Details
- Journal
- Journal of Neuro-Oncology
- Published
- 2025-11-10
- DOI
- https://doi.org/10.1007/s11060-025-05282-9
- Citations
- 1
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.63