Jujuboside A Alleviates Facial Allodynia of <scp>CCI</scp> ‐ <scp>ION</scp> Rats by Inhibiting the Expression of <scp>P2X7</scp> Receptor in the Spinal Trigeminal Subnucleus Caudalis
These findings suggest the potential benefits of Jujuboside A in trigeminal neuralgia treatment through suppression of pyroptosis by inhibition of the nucleotide-binding domain, leucine-rich family, and pyrin domain-containing 3/caspase-1 pathway mediated by the P2X7 receptor in the spinal trigeminal subnucleus caudalis.
Authors
- Wei Xiong (ORCID: https://orcid.org/0000-0001-8870-8289)
- Zhiqiang Ouyang
- Jingyan Zhang (ORCID: https://orcid.org/0000-0001-5416-9766)
- Yongli Wu (ORCID: https://orcid.org/0000-0001-9774-453X)
- Yuanyi Zhang (ORCID: https://orcid.org/0000-0002-2609-5672)
- Yun Gao (ORCID: https://orcid.org/0000-0003-2519-9979)
- Yuhan Zhou (ORCID: https://orcid.org/0000-0003-0206-9290)
- Lijuan Liu (ORCID: https://orcid.org/0000-0001-8068-8498)
- Min Zhou (ORCID: https://orcid.org/0000-0001-5650-4628)
- Wei Han (ORCID: https://orcid.org/0000-0002-9143-903X)
- Yanting Qiu (ORCID: https://orcid.org/0000-0003-2759-4323)
- Xinyue Pu
Institutions
- Nanchang University (CN)
- Jiangxi Provincial People's Hospital (CN)
- Jiangxi Provincial Institute of Water Sciences (CN)
- Yiwu Science and Technology Research Institute (CN)
Publication Details
- Journal
- Journal of Oral Pathology and Medicine
- Published
- 2025-11-10
- DOI
- https://doi.org/10.1111/jop.70085
- Primary Topic
- Ziziphus Jujuba Studies and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00