Towards Efficient Patient Recruitment for Clinical Trials: Application of a Prompt-Based Learning Model

Our results demonstrate that integrating ontology-based extractive summarization with prompt-based LLMs can substantially improve eligibility classification. The summarization step enhanced model focus and interpretability, particularly for long or ambiguous narratives. This pipeline offers a scalable and adaptable framework for clinical trial automation and has the potential for real-world integration with electronic medical record matching systems.

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Publication Details

Journal
Healthcare Informatics Research
Published
2025-10-31
DOI
https://doi.org/10.4258/hir.2025.31.4.367
Primary Topic
Machine Learning in Healthcare
Type
article
Field-Weighted Citation Impact
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article

Towards Efficient Patient Recruitment for Clinical Trials: Application of a Prompt-Based Learning Model

Seyed Mostafa Fakhrahmad, Mojdeh Rahmanian, Seyed Asadoullah Mousavi
Healthcare Informatics Research
Machine Learning in Healthcare
article

Towards Efficient Patient Recruitment for Clinical Trials: Application of a Prompt-Based Learning Model

Seyed Mostafa Fakhrahmad, Mojdeh Rahmanian, Seyed Asadoullah Mousavi
article en

Abstract

Our results demonstrate that integrating ontology-based extractive summarization with prompt-based LLMs can substantially improve eligibility classification. The summarization step enhanced model focus and interpretability, particularly for long or ambiguous narratives. This pipeline offers a scalable and adaptable framework for clinical trial automation and has the potential for real-world integration with electronic medical record matching systems.

Healthcare Informatics ResearchVol. 31(4)
Shiraz University (IR), Shiraz University of Medical Sciences (IR)
Openalex Percentile: Top 82%
Machine Learning in Healthcare
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