Interactions between Tau Phosphorylation and Endoplasmic Reticulum Stress in Diabetic Nephropathy
Our findings demonstrate that site-specific tau phosphorylation is associated with renal injury in DN and may serve as a potential marker of disease severity. The interplay between tau phosphorylation and ER stress appears to contribute to disease progression. Targeting tau phosphorylation and its upstream stress pathways may offer new therapeutic strategies for DN.
Authors
- SeongWoo Lee (ORCID: https://orcid.org/0000-0003-3565-5050)
- Su Ho Jo
- Eun Soo Lee (ORCID: https://orcid.org/0000-0002-1973-0930)
- Choon Hee Chung (ORCID: https://orcid.org/0000-0003-1144-7206)
- Ji-Hye Lee (ORCID: https://orcid.org/0000-0003-3269-3844)
- Eun Young Lee (ORCID: https://orcid.org/0000-0001-6975-8627)
- Jeong Suk Kang (ORCID: https://orcid.org/0009-0001-9215-5637)
Institutions
- Yonsei University (KR)
- Soonchunhyang University (KR)
Publication Details
- Journal
- Diabetes & Metabolism Journal
- Published
- 2025-11-11
- DOI
- https://doi.org/10.4093/dmj.2024.0618
- Primary Topic
- Chronic Kidney Disease and Diabetes
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Research Foundation
- National Research Foundation of Korea