Reducing Daunorubicin in Induction Therapy in Children With B-Lineage ALL With Favorable Prognosis: Results of Phase III Trial AIEOP-BFM ALL 2009

A reduced DNR dose during induction did not compromise the outcome of patients with favorable prognostic factors but did diminish infectious toxicity indicated by the lower rate of invasive fungal infections.

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Publication Details

Journal
Journal of Clinical Oncology
Published
2025-11-10
DOI
https://doi.org/10.1200/jco-25-01357
Primary Topic
Acute Lymphoblastic Leukemia research
Type
article
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article

Reducing Daunorubicin in Induction Therapy in Children With B-Lineage ALL With Favorable Prognosis: Results of Phase III Trial AIEOP-BFM ALL 2009

Valentino Conter, Martin Stanulla, Christian Flotho, Draga Barbaric et al.
Journal of Clinical Oncology
Acute Lymphoblastic Leukemia research
article

Reducing Daunorubicin in Induction Therapy in Children With B-Lineage ALL With Favorable Prognosis: Results of Phase III Trial AIEOP-BFM ALL 2009

Valentino Conter, Martin Stanulla, Christian Flotho, Draga Barbaric, Martin Schrappe, Franco Locatelli, H. Gottschalk, Shai Izraeli, Luciano Dalla‐Pozza, Martin Zimmermann, Jan Starý, Daniela Silvestri, Gunnar Cario, Barbara Buldini, Andrea Biondi, Jean‐Pierre Bourquin, Carmelo Rizzari, Michael Dworzak, Nicole Bodmer, Anja Möricke, Maria Grazia Valsecchi, Sarah Elitzur, Andishe Attarbaschi, Anke K. Bergmann
article en

Abstract

A reduced DNR dose during induction did not compromise the outcome of patients with favorable prognostic factors but did diminish infectious toxicity indicated by the lower rate of invasive fungal infections.

Journal of Clinical OncologyVol. 43(35)
Università Cattolica del Sacro Cuore (IT), University of Padua (IT), Charles University (CZ), University of Würzburg (DE), University Medical Center Freiburg (DE), Children's Hospital at Westmead (AU), UNSW Sydney (AU), Medizinische Hochschule Hannover (DE), Schneider Children's Medical Center (IL), Azienda Ospedaliera San Gerardo (IT), University Hospital Schleswig-Holstein (DE), Institute of Human Genetics (PL), Bambino Gesù Children's Hospital (IT), St Anna Children's Hospital (AT), Sydney Children's Hospital (AU), University Children's Hospital Zurich (CH), Istituti di Ricovero e Cura a Carattere Scientifico (IT), University of Lübeck (DE)
Openalex Percentile: Top 56%
Acute Lymphoblastic Leukemia research
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