Rare Genetic Variants of Cell Adhesion Molecules in Transgender Men Suggest a Potential Role in Gender Dysphoria

Our study shows that rare variants in cell adhesion genes, previously reported in TW, are also prominent in TM. These findings may help guide further investigations into genes that could be relevant to neurodevelopmental pathways, including those involved in brain sexual differentiation. .

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Publication Details

Journal
Sexual Development
Published
2025-11-07
DOI
https://doi.org/10.1159/000549011
Primary Topic
Wnt/β-catenin signaling in development and cancer
Type
article
Field-Weighted Citation Impact
0.00
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article

Rare Genetic Variants of Cell Adhesion Molecules in Transgender Men Suggest a Potential Role in Gender Dysphoria

Özden Altıok Clark, Ahmet Okay Çağlayan, Duygu Onur Cura, Tufan Çankaya et al.
Sexual Development
Wnt/β-catenin signaling in development and cancer
article

Rare Genetic Variants of Cell Adhesion Molecules in Transgender Men Suggest a Potential Role in Gender Dysphoria

Özden Altıok Clark, Ahmet Okay Çağlayan, Duygu Onur Cura, Tufan Çankaya, Ayfer Ülgenalp, Leyla Rezan Aydin
article en

Abstract

Our study shows that rare variants in cell adhesion genes, previously reported in TW, are also prominent in TM. These findings may help guide further investigations into genes that could be relevant to neurodevelopmental pathways, including those involved in brain sexual differentiation. .

Sexual DevelopmentVol. 19(1-6)
Dokuz Eylül University (TR), Akdeniz University (TR), Pamukkale University (TR)
Openalex Percentile: Top 70%
Wnt/β-catenin signaling in development and cancer
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