Electrochemical Dehydrocarboxylation of Alcohols Mediated by Cu <sub>0.5</sub> Ni <sub>0.5</sub> -LDH
Oxidation of primary alcohols to produce the corresponding carboxylic acids is a fundamental reaction in organic synthesis. In this article, we report a process for the oxidation of primary alcohols using chemically modified electrodes. This is characterized as a green, mild, oxidant-free, and easy-to-operate process with high isolation yields and good functional group tolerance. A series of controlled experiments demonstrate the reaction mechanism.
Authors
- Lin‐Bao Zhang (ORCID: https://orcid.org/0000-0002-8334-4188)
- Weisi Guo (ORCID: https://orcid.org/0000-0001-6688-4679)
- Hongtao Gao (ORCID: https://orcid.org/0000-0001-9205-0301)
- Wenlong Yang (ORCID: https://orcid.org/0000-0003-0107-7694)
- Ming Li (ORCID: https://orcid.org/0000-0003-4906-936X)
- Xinyu Zhang (ORCID: https://orcid.org/0000-0003-3830-4096)
- Jiaxiu Liu
- Fengjuan Guo
Institutions
- Qingdao University of Science and Technology (CN)
Publication Details
- Journal
- Organic Letters
- Published
- 2025-11-10
- DOI
- https://doi.org/10.1021/acs.orglett.5c03569
- Primary Topic
- Oxidative Organic Chemistry Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00