Feasibility and Safety of Intraoperative Application of Porous Hydroxyapatite/Collagen Composites to Prevent Craniotomy Defects: A Pilot Study
This study demonstrated the feasibility and safety of intraoperative implantation of porous HAp/Col as a bone filler to prevent bone defects caused by craniotomy. Porous HAp/Col is an absorbable artificial bone that can serve as an effective substitute for ABP, with the potential to safely maintain long-term esthetics and strength.
Authors
- Mizuki Kambara (ORCID: https://orcid.org/0000-0001-6710-9092)
- Kentaro Hayashi (ORCID: https://orcid.org/0000-0001-5139-7560)
- Tomohiro Yamasaki (ORCID: https://orcid.org/0000-0003-4477-3286)
- Masahiro Uchimura (ORCID: https://orcid.org/0009-0001-2516-1404)
- Tsutomu Yoshikane (ORCID: https://orcid.org/0000-0002-1311-8396)
Institutions
- Shimane University (JP)
Publication Details
- Journal
- Operative Neurosurgery
- Published
- 2025-11-10
- DOI
- https://doi.org/10.1227/ons.0000000000001847
- Primary Topic
- Bone Tissue Engineering Materials
- Type
- article
- Field-Weighted Citation Impact
- 0.00