Identification and validation of the important role of tryptophan-related gene CYP1B1 in the development and progression of sepsis
CYP1B1 is involved in tryptophan metabolism and its upregulation can promote the progression and development of sepsis through activating monocytes.
Authors
- Huirong Hu
- Zhi-Yuan Chen (ORCID: https://orcid.org/0000-0002-9365-9976)
- Lihong Chen (ORCID: https://orcid.org/0000-0002-3230-5736)
- Wei‐Ru Lin
- Yanhui Wang (ORCID: https://orcid.org/0009-0003-0813-1726)
Institutions
- Fujian Medical University (CN)
- Fujian Women and Children Hospital (CN)
- Maternity and Children's Hospital (SA)
- The 180th Hospital of PLA (CN)
- Second Affiliated Hospital of Fujian Medical University (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-11-10
- DOI
- https://doi.org/10.1371/journal.pone.0335944
- Primary Topic
- Tryptophan and brain disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00