Paravertebral or Serratus Anterior Plane Block Combined with Interpectoral Blocks versus Paravertebral Block for Mastectomy: A Cluster-randomized Trial of 1,507 Patients
Paravertebral or serratus anterior plane blocks combined with PECS I blocks were not superior to paravertebral block alone in reducing high opioid use after bilateral mastectomy with expander reconstruction. All three block approaches are acceptable techniques for this procedure. Choice of block should be based on clinician expertise, patient-specific factors, and safety considerations.
Authors
- Hanae K. Tokita (ORCID: https://orcid.org/0000-0001-5806-1138)
- Aisha Baqai-Stern
- Alexandra Lewis
- Geema Masson
- Andrew Julian Vickers (ORCID: https://orcid.org/0000-0003-1525-6503)
- Vinay Puttanniah
- Jacob Jackson
- Storm Horine (ORCID: https://orcid.org/0000-0002-6929-8007)
- Howard Teng (ORCID: https://orcid.org/0000-0001-5378-7300)
- Brett A. Simon (ORCID: https://orcid.org/0000-0001-8607-1800)
- Melissa J. Assel (ORCID: https://orcid.org/0009-0004-6344-9371)
- Joanna Serafin (ORCID: https://orcid.org/0000-0002-1097-3338)
- Danielle Nadav
- Justin Kim (ORCID: https://orcid.org/0000-0002-6544-6797)
- Cosmin Gauran
- Aron Legler
- Lee Hingula
- Taylor M. McCready (ORCID: https://orcid.org/0000-0002-7576-1707)
- Jonas A. Nelson (ORCID: https://orcid.org/0000-0003-0329-4422)
- Emily Lin (ORCID: https://orcid.org/0009-0004-9765-0946)
- Cameran Vakassi
- M. F. Scanlon
- Tracy-Ann Moo
- Leslie Sarraf (ORCID: https://orcid.org/0000-0002-9258-5450)
- John W. Hagen
Institutions
- Memorial Sloan Kettering Cancer Center (US)
Publication Details
- Journal
- Anesthesiology
- Published
- 2025-11-10
- DOI
- https://doi.org/10.1097/aln.0000000000005842
- Primary Topic
- Anesthesia and Pain Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00