Importance of Perioperative Antibiotic Timing in Elective and Emergency Colorectal Surgery
In both elective and emergency colorectal surgery, early or late antibiotic administration relative to incision was associated with increased 30-day mortality. The lowest risk occurred when antibiotics were administered approximately 50 minutes before incision. These findings support optimising perioperative antibiotic timing to improve postoperative outcomes in emergency colorectal surgery.
Authors
- Rami Sommerstein (ORCID: https://orcid.org/0000-0003-1011-6878)
- Stephan Harbarth (ORCID: https://orcid.org/0000-0002-3551-1025)
- Sarah Peisl (ORCID: https://orcid.org/0000-0002-1215-6964)
- Andreas F. Widmer (ORCID: https://orcid.org/0000-0002-7661-5824)
- Guido Beldi (ORCID: https://orcid.org/0000-0002-9914-3807)
- Beat Schnüriger (ORCID: https://orcid.org/0000-0002-1672-2775)
Institutions
- University of Bern (CH)
- University of Lucerne (CH)
- University of Basel (CH)
- University Hospital of Bern (CH)
- University Hospital of Basel (CH)
- University Hospital of Geneva (CH)
- Geneva College (US)
Publication Details
- Journal
- Journal of the American College of Surgeons
- Published
- 2025-11-10
- DOI
- https://doi.org/10.1097/xcs.0000000000001686
- Primary Topic
- Enhanced Recovery After Surgery
- Type
- article
- Field-Weighted Citation Impact
- 0.00