PRC1, CDCA3, and CDC20 are upregulated and Treg numbers are decreased in canine massive hepatocellular carcinoma
PRC1, CDCA3, and CDC20 were upregulated and were identified as candidate oncogenic genes in canine massive HCC. Downregulation of Tregs may be associated with prognosis in canine massive HCC.
Authors
- Yasumasa Iimori (ORCID: https://orcid.org/0000-0003-2575-2287)
- Toshiyuki T. Tanaka (ORCID: https://orcid.org/0000-0002-7911-913X)
- Tomoki Motegi (ORCID: https://orcid.org/0000-0002-6811-0973)
- Hideo Akiyoshi (ORCID: https://orcid.org/0000-0002-5945-0300)
Institutions
- Tokyo University of Agriculture (JP)
- Purdue University West Lafayette (US)
- Willows Veterinary Centre and Referral Service (GB)
- Osaka Metropolitan University (JP)
- Tokyo University of Agriculture and Technology (JP)
Publication Details
- Journal
- BMC Veterinary Research
- Published
- 2025-11-10
- DOI
- https://doi.org/10.1186/s12917-025-05103-1
- Primary Topic
- Veterinary Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Japan Society for the Promotion of Science