Analysis of the associations between DNA methylation and clinical features reveals the potential oncogenic effect of CFAP52 in esophageal squamous cell cancer
Collectively, our investigations show that DNA methylation is associated with sex and alcohol consumption in ESCC. Besides, DNA methylation is linked to ESCC prognosis. Moreover, we uncover the potential oncogenic role of CFAP52 in ESCC.
Authors
- Mengzhu Lv (ORCID: https://orcid.org/0000-0002-7804-2636)
- Yan Wang (ORCID: https://orcid.org/0000-0003-2563-255X)
- Qimin Zhan (ORCID: https://orcid.org/0000-0002-1731-938X)
- Guangchao Wang (ORCID: https://orcid.org/0000-0003-4285-7144)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking University (CN)
- Soochow University (CN)
- National Cancer Center (US)
- Peking University Cancer Hospital (CN)
- Shenzhen Bay Laboratory (CN)
- Peking University International Hospital (CN)
Publication Details
- Journal
- Cancer Cell International
- Published
- 2025-11-10
- DOI
- https://doi.org/10.1186/s12935-025-03934-4
- Primary Topic
- Esophageal Cancer Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Chinese Academy of Medical Sciences
- Peking University