Collateral status may modify the effect of methylprednisolone in endovascular treatment for acute ischemic stroke: a post hoc analysis of the MARVEL randomized trial

Collateral status modifies the effect of methylprednisolone in AIS patients undergoing EVT. These hypothesis-generating findings suggest that patients with poor collaterals may derive benefit from methylprednisolone, potentially guiding adjunctive therapy decisions. Prospective validation is warranted before clinical application.

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Publication Details

Journal
International Journal of Surgery
Published
2025-11-06
DOI
https://doi.org/10.1097/js9.0000000000003924
Citations
1
Primary Topic
Acute Ischemic Stroke Management
Type
article
Field-Weighted Citation Impact
1.35
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article

Collateral status may modify the effect of methylprednisolone in endovascular treatment for acute ischemic stroke: a post hoc analysis of the MARVEL randomized trial

Wenjie Zi, Hong Zhu, Johannes Kaesmacher, Zhenxuan Tian et al.
1 citations
International Journal of Surgery
Acute Ischemic Stroke Management
1.35
article

Collateral status may modify the effect of methylprednisolone in endovascular treatment for acute ischemic stroke: a post hoc analysis of the MARVEL randomized trial

Wenjie Zi, Hong Zhu, Johannes Kaesmacher, Zhenxuan Tian, Linyu Li, Jiaxing Song, Thanh N. Nguyen, Boyu Chen, Yonghan He, Changchun Jiang, Chengsong Yue, Changwei Guo, W. F. Mader, Zhuang Li, Shitao Fan, Gaoming Li, Xiaolei Shi, Jie Yang, Shihai Yang
article en
1 citations

Abstract

Collateral status modifies the effect of methylprednisolone in AIS patients undergoing EVT. These hypothesis-generating findings suggest that patients with poor collaterals may derive benefit from methylprednisolone, potentially guiding adjunctive therapy decisions. Prospective validation is warranted before clinical application.

International Journal of SurgeryVol. 112(2)
Boston University (US), University of Bern (CH), Boston Medical Center (US), Army Medical University (CN), Kunming Medical University (CN), University Hospital of Bern (CH), Mianyang Third People's Hospital (CN), Centre Hospitalier Universitaire de Tours (FR), Clinical Investigation Center Plurithematic Tours (FR), Centre de Recherche en Sciences et Technologies de l'Information et de la Communication (FR), Qujing Normal University (CN), Sichuan Mianyang 404 Hospital (CN), Xinqiao Hospital (CN), Baotou Central Hospital (CN), Le Studium (FR), Liuyang City Maternal and Child Health Hospital (CN)
Openalex Percentile: Top 14%
Acute Ischemic Stroke Management
1.35
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