Crosstalk between the Wnt signaling pathway and axon guidance molecules reveals a novel signature for accurately predicting diagnosis, prognosis, and immune landscape in colorectal cancer
The WARGsSig provides a potential tool for predicting diagnosis, prognosis, molecular subtypes, and immune context in CRC. These findings offer mechanistic insights and a foundation for future research, with promising implications for risk stratification and personalized treatment strategies.
Authors
- Yan Zheng (ORCID: https://orcid.org/0000-0003-1788-9179)
- Yang Liu (ORCID: https://orcid.org/0000-0003-4874-4773)
- Tiegang Li (ORCID: https://orcid.org/0000-0002-7119-7897)
- Yufang Hou
- Silin Lv
- Zifan Zeng (ORCID: https://orcid.org/0000-0002-1720-905X)
- Min Yang (ORCID: https://orcid.org/0000-0002-3827-5961)
- Mingxuan Zhou
- Fang Zhang (ORCID: https://orcid.org/0000-0002-5314-4409)
- Wenyi Zhao (ORCID: https://orcid.org/0009-0003-4073-6573)
- Yixin Zhou (ORCID: https://orcid.org/0000-0001-7303-2255)
- Zhaohui Zhu (ORCID: https://orcid.org/0000-0001-9931-850X)
- Jinbao Zong
- Xinyi Ren (ORCID: https://orcid.org/0009-0003-8514-5988)
- Yuexia Che
Institutions
- Qingdao University (CN)
- Minzu University of China (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Affiliated Hospital of Qingdao University (CN)
Publication Details
- Journal
- International Journal of Surgery
- Published
- 2025-11-07
- DOI
- https://doi.org/10.1097/js9.0000000000003853
- Primary Topic
- Wnt/β-catenin signaling in development and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00