Retrospective cohort analysis of low-molecular-weight heparin versus non-vitamin K antagonist oral anticoagulants for venous thromboembolism prophylaxis across racial groups in hospitalized trauma patients
DOACs are associated with higher VTE and mortality rates than LMWH in patients with major trauma, with African American and Asian patients experiencing disproportionately higher risks than Caucasians. These findings contradict the notion that certain racial groups might benefit more from DOAC prophylaxis and suggest that LMWH should remain the preferred option for VTE prophylaxis in patients with major trauma across all racial groups.
Authors
- Chi‐Tung Cheng (ORCID: https://orcid.org/0000-0002-2697-4642)
- Ming-Jer Hsieh
- Dong‐Yi Chen (ORCID: https://orcid.org/0000-0002-9544-5496)
- Chieh-Yu Chang (ORCID: https://orcid.org/0000-0002-9288-0943)
- Jen‐Fu Huang (ORCID: https://orcid.org/0000-0001-8185-8372)
- Chih-Po Hsu (ORCID: https://orcid.org/0000-0002-4737-2800)
- Chien‐Hung Liao (ORCID: https://orcid.org/0000-0003-2812-9773)
- I-Chang Hsieh (ORCID: https://orcid.org/0000-0003-4621-9609)
- Ya-Chiao Lin
Institutions
- Ministry of Health and Welfare (KR)
- Chang Gung University (TW)
- Jen-Ai Hospital (TW)
- Chang Gung Memorial Hospital (TW)
- Linkou Chang Gung Memorial Hospital (TW)
- Ministry of Health and Welfare (TW)
Publication Details
- Journal
- International Journal of Surgery
- Published
- 2025-11-07
- DOI
- https://doi.org/10.1097/js9.0000000000003882
- Primary Topic
- Venous Thromboembolism Diagnosis and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00