A Minimum Information about a High Containment Laboratory Experiment (MIHCLE) reporting standard

Experiments with high-risk pathogens are routinely conducted under strict conditions of biosafety and biosecurity. In this Comment, we propose a Minimum Information about a High Containment Laboratory Experiment (MIHCLE) reporting standard. Although conceived particularly for work in biosafety level (BSL) 4 laboratories, it can be generally applicable to any research performed in both high (BSL-3) and maximum (BSL-4) containment facilities.

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Publication Details

Journal
Nature Methods
Published
2025-11-10
DOI
https://doi.org/10.1038/s41592-025-02862-5
Citations
1
Primary Topic
Bacillus and Francisella bacterial research
Type
article
Field-Weighted Citation Impact
0.81

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article

A Minimum Information about a High Containment Laboratory Experiment (MIHCLE) reporting standard

Åsa Björndal, Romain David, Kurt Zatloukal, Jonathan J. Ewbank et al.
1 citations
Nature Methods
Bacillus and Francisella bacterial research
0.81
article

A Minimum Information about a High Containment Laboratory Experiment (MIHCLE) reporting standard

Åsa Björndal, Romain David, Kurt Zatloukal, Jonathan J. Ewbank, Bernadett Pályi, József Pete
article en
1 citations

Abstract

Experiments with high-risk pathogens are routinely conducted under strict conditions of biosafety and biosecurity. In this Comment, we propose a Minimum Information about a High Containment Laboratory Experiment (MIHCLE) reporting standard. Although conceived particularly for work in biosafety level (BSL) 4 laboratories, it can be generally applicable to any research performed in both high (BSL-3) and maximum (BSL-4) containment facilities.

Nature MethodsVol. 23(2)
Public Health Agency of Sweden (SE), Medical University of Graz (AT), European Research Council (BE), Government of Hungary (HU), National Public Health and Medical Officer Service (HU), Association des Operateurs Postaux Publics Europeens (BE), Institut National de Santé Publique (TN)
European Commission, Public Health Agency, Institut National de la Santé et de la Recherche Médicale, Karl-Franzens-Universität Graz, Medizinische Universität Graz, Folkhälsomyndigheten, HORIZON EUROPE Framework Programme
Openalex Percentile: Top 22%
Bacillus and Francisella bacterial research
0.81
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