Diagnostic Potential of Circulating lncRNA SNHG5 in Osteoporotic Fractures and Its Mechanistic Role in Accelerating Fracture Healing
SNHG5 indirectly enhances osteoblast activity by negatively regulating miR-23a-3p, thereby promoting fracture healing. Our study could furnish both theoretical and experimental support for the discovery of innovative treatment targets.
Authors
- Xiaowei Jiang (ORCID: https://orcid.org/0000-0002-6030-1249)
- Lei Shang (ORCID: https://orcid.org/0000-0003-0470-0066)
- Chen Shao (ORCID: https://orcid.org/0000-0002-6899-5353)
- Jiaojiao Chen (ORCID: https://orcid.org/0000-0002-9041-0307)
- Li Jin (ORCID: https://orcid.org/0000-0002-8331-6953)
- Liang Han (ORCID: https://orcid.org/0000-0003-1081-0077)
Institutions
- Xuzhou Medical College (CN)
- Xuzhou Central Hospital (CN)
- Second Affiliated Hospital of Xuzhou Medical College (CN)
Publication Details
- Journal
- Journal of Investigative Surgery
- Published
- 2025-11-10
- DOI
- https://doi.org/10.1080/08941939.2025.2577389
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 0.00