Uterine Leiomyosarcoma Diagnosed at Caesarean Myomectomy: A Case Report

A 33-year-old patient had a history of a uterine leiomyoma that was first diagnosed incidentally on a dating scan in a previous pregnancy. This was further confirmed on different ultrasound scans after birth, and her main symptom was abnormal uterine bleeding. When she was due for further imaging and hysteroscopy, she was already eight weeks pregnant. Throughout pregnancy, the leiomyoma was growing on serial ultrasound scans, but she was not symptomatic. During her elective caesarean section (CS), a pedunculated leiomyoma was protruding from the posterior wall of the lower uterine segment and was excised and sent for histopathology. This was reported as a uterine leiomyosarcoma (ULMS), and she was referred to gynaecological oncology for management. Following this, she had staging investigations, which showed no metastasis. She proceeded to have a hysterectomy, and the histology confirmed complete treatment.

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Publication Details

Journal
Cureus
Published
2025-11-10
DOI
https://doi.org/10.7759/cureus.96468
Primary Topic
Uterine Myomas and Treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Uterine Leiomyosarcoma Diagnosed at Caesarean Myomectomy: A Case Report

Richard Peevor, Khalid Alloush, Tabitha Oosterhouse, Sara El Hamamy
Cureus
Uterine Myomas and Treatments
article

Uterine Leiomyosarcoma Diagnosed at Caesarean Myomectomy: A Case Report

Richard Peevor, Khalid Alloush, Tabitha Oosterhouse, Sara El Hamamy
article en

Abstract

A 33-year-old patient had a history of a uterine leiomyoma that was first diagnosed incidentally on a dating scan in a previous pregnancy. This was further confirmed on different ultrasound scans after birth, and her main symptom was abnormal uterine bleeding. When she was due for further imaging and hysteroscopy, she was already eight weeks pregnant. Throughout pregnancy, the leiomyoma was growing on serial ultrasound scans, but she was not symptomatic. During her elective caesarean section (CS), a pedunculated leiomyoma was protruding from the posterior wall of the lower uterine segment and was excised and sent for histopathology. This was reported as a uterine leiomyosarcoma (ULMS), and she was referred to gynaecological oncology for management. Following this, she had staging investigations, which showed no metastasis. She proceeded to have a hysterectomy, and the histology confirmed complete treatment.

CureusVol. 17(11)
Betsi Cadwaladr University Health Board (GB)
Betsi Cadwaladr University Health Board
Openalex Percentile: Top 58%
Uterine Myomas and Treatments
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Uterine Leiomyosarcoma Diagnosed at Caesarean Myomectomy: A Case Report — Richard Peevor, Khalid Alloush, et al. · Cureus (2025) | TGRS Research Map | TGRS