Clinical risk factors, antimicrobial therapy, and virulence-associated mortality in patients with extensively drug-resistant or pan-drug-resistant (XDR/PDR) Pseudomonas aeruginosa pulmonary infections

Respiratory diseases and cardiovascular diseases are independent risk factors for 30-day mortality in patients with XDR/PDR-P. aeruginosa pulmonary infections. Virulence characteristics such as strong biofilm formation and low serum killing ability were significantly associated with 30-day mortality, suggesting their critical role in disease progression.