von Willebrand factor and fibrin monomer - induced septic shock coagulation typing: Clinical comparison between thrombotic thrombocytopenic purpura - like syndrome and sepsis - induced coagulopathy with prognostic implications

TTP-like syndrome and SIC represent heterogeneous coagulation phenotypes in septic shock, with differences in biomarkers, organ injury, and prognosis. A vWF- and FM-guided subtype classification may improve individualized treatment strategies and prognostic management.

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Publication Details

Journal
Thrombosis Research
Published
2025-11-10
DOI
https://doi.org/10.1016/j.thromres.2025.109536
Primary Topic
Complement system in diseases
Type
article
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0.00
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article

von Willebrand factor and fibrin monomer - induced septic shock coagulation typing: Clinical comparison between thrombotic thrombocytopenic purpura - like syndrome and sepsis - induced coagulopathy with prognostic implications

H. Zhang, Weili Zhao, Qingqing Huang, Jinxi Yue et al.
Thrombosis Research
Complement system in diseases
article

von Willebrand factor and fibrin monomer - induced septic shock coagulation typing: Clinical comparison between thrombotic thrombocytopenic purpura - like syndrome and sepsis - induced coagulopathy with prognostic implications

H. Zhang, Weili Zhao, Qingqing Huang, Jinxi Yue, Wangzheqi Zhang, Jingjing Zhang, Zongfang Ren, Yi Liu, Bin Zhang, Xiaohong Wan, Han Chen, Jin Yang
article en

Abstract

TTP-like syndrome and SIC represent heterogeneous coagulation phenotypes in septic shock, with differences in biomarkers, organ injury, and prognosis. A vWF- and FM-guided subtype classification may improve individualized treatment strategies and prognostic management.

Thrombosis ResearchVol. 256
Universiti Sains Malaysia (MY), Zunyi Medical University (CN), Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Kunming Medical University (CN)
Openalex Percentile: Top 65%
Complement system in diseases
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von Willebrand factor and fibrin monomer - induced septic shock coagulation typing: Clinical comparison between thrombotic thrombocytopenic purpura - like syndrome and sepsis - induced coagulopathy with prognostic implications — H. Zhang, Weili Zhao, et al. · Thrombosis Research (2025) | TGRS Research Map | TGRS