Peri‐operative hypersensitivity reactions to neuromuscular blocking drugs in New Zealand 2013–2019: a retrospective observational study

We found a significant difference between the rates of peri-operative hypersensitivity reactions with rocuronium and suxamethonium vs. atracurium. The increased risk of a peri-operative hypersensitivity reaction is a factor that should be weighed against the benefits of using suxamethonium or rocuronium. Females may be higher risk than males of reacting to neuromuscular blocking drugs.

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Publication Details

Journal
Anaesthesia
Published
2025-11-10
DOI
https://doi.org/10.1111/anae.70058
Primary Topic
Anesthesia and Sedative Agents
Type
article
Field-Weighted Citation Impact
0.00
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article

Peri‐operative hypersensitivity reactions to neuromuscular blocking drugs in New Zealand 2013–2019: a retrospective observational study

K. Pedersen, Henry E. Wang, Johan van Schalkwyk, Peter Cooke et al.
Anaesthesia
Anesthesia and Sedative Agents
article

Peri‐operative hypersensitivity reactions to neuromuscular blocking drugs in New Zealand 2013–2019: a retrospective observational study

K. Pedersen, Henry E. Wang, Johan van Schalkwyk, Peter Cooke, Kim Phillips
article en

Abstract

We found a significant difference between the rates of peri-operative hypersensitivity reactions with rocuronium and suxamethonium vs. atracurium. The increased risk of a peri-operative hypersensitivity reaction is a factor that should be weighed against the benefits of using suxamethonium or rocuronium. Females may be higher risk than males of reacting to neuromuscular blocking drugs.

AnaesthesiaVol. 81(4)
Canterbury Health Laboratories (NZ), Palmerston North Hospital (NZ)
Openalex Percentile: Top 49%
Anesthesia and Sedative Agents
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