Antiviral and immunomodulatory effects of Chaihu Guizhi decoction in an acute depression‐like mouse model infected with influenza A virus
CGD has a therapeutic effect in mice with depression-like symptoms infected with IAV, increasing the levels of DA and NE, downregulating M gene expression, calming the cytokine storm, and preserving the homeostasis of Th17/Treg cells.
Authors
- Dongxue Ye
- Meiyi Liu
- Shensi Qian
- Xiaoyun Liu (ORCID: https://orcid.org/0000-0002-7497-580X)
- Rong Rong (ORCID: https://orcid.org/0000-0001-6261-9202)
- Ran Shi (ORCID: https://orcid.org/0000-0002-9736-2686)
- Yong Yang
- Jia Yang (ORCID: https://orcid.org/0000-0002-3992-4070)
Institutions
- Shandong University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Animal Models and Experimental Medicine
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1002/ame2.70095
- Citations
- 1
- Primary Topic
- Tryptophan and brain disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.58
Funders
- Shandong University
- National Natural Science Foundation of China
- Natural Science Foundation of Shandong Province