Mechanism of Duzhong Bushen Formula Regulating MAPK/AP-1 Pathway to Improve Lumbar Intervertebral Disc Degeneration: Evidencefrom Network Pharmacology and In Vivo Experiment in Rats

DBF may be a promising multi-target therapeutic agent for the treatment of IDD, particularly in cases involving kidney deficiency and blood stasis.

Authors

Yao Zhou (ORCID: https://orcid.org/0000-0002-6527-9802)
Ting Jiang (ORCID: https://orcid.org/0000-0002-6847-0020)
Hao Lv (ORCID: https://orcid.org/0000-0001-6758-8492)
Yán Wāng (ORCID: https://orcid.org/0000-0002-2940-3300)
Xingyu Wang
Yi Wang (ORCID: https://orcid.org/0000-0002-2067-5465)
Lei Shi (ORCID: https://orcid.org/0009-0003-8190-7711)
Yinghao Zhu
Qingsong Chu

Institutions

Anhui University of Traditional Chinese Medicine (CN)

Publication Details

Journal: Combinatorial Chemistry & High Throughput Screening
Published: 2025-11-05
DOI: https://doi.org/10.2174/0113862073409567251008054328
Primary Topic: Spine and Intervertebral Disc Pathology
Type: article
Field-Weighted Citation Impact: 0.00

Controls

|||

ALL TIME

JAN

FEB

MAR

APR

MAY

JUN

JUL

AUG

SEP

OCT

article

Mechanism of Duzhong Bushen Formula Regulating MAPK/AP-1 Pathway to Improve Lumbar Intervertebral Disc Degeneration: Evidencefrom Network Pharmacology and In Vivo Experiment in Rats

Yao Zhou, Ting Jiang, Hao Lv, Yán Wāng et al.

Nov 5, 2025

Combinatorial Chemistry & High Throughput Screening

Spine and Intervertebral Disc Pathology

article

Mechanism of Duzhong Bushen Formula Regulating MAPK/AP-1 Pathway to Improve Lumbar Intervertebral Disc Degeneration: Evidencefrom Network Pharmacology and In Vivo Experiment in Rats

Yao Zhou, Ting Jiang, Hao Lv, Yán Wāng, Xingyu Wang, Yi Wang, Lei Shi, Yinghao Zhu, Qingsong Chu

November 5, 2025article en

Abstract

DBF may be a promising multi-target therapeutic agent for the treatment of IDD, particularly in cases involving kidney deficiency and blood stasis.

Combinatorial Chemistry & High Throughput ScreeningVol. 29

Anhui University of Traditional Chinese Medicine (CN)

Openalex Percentile: Top 54%

Spine and Intervertebral Disc Pathology

DOI Source OpenAlex

AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Mechanism of Duzhong Bushen Formula Regulating MAPK/AP-1 Pathway to Improve Lumbar Intervertebral Disc Degeneration: Evidencefrom Network Pharmacology and In Vivo Experiment in Rats — Yao Zhou, Ting Jiang, et al. · Combinatorial Chemistry & High Throughput Screening (2025) | TGRS Research Map | TGRS