Sex‐Based Differences in Coronary Physiological Assessment in Patients With Severe Aortic Stenosis
Female sex is an independent predictor of FFR/iFR discordance in severe AS, manifesting exclusively as the FFR-negative/iFR-positive pattern. This finding suggests sex-specific differences in coronary microvascular function that may influence revascularization decisions. Recognition of these differences might be important for optimal management of coronary disease in severe AS.
Authors
- Łukasz Niewiara (ORCID: https://orcid.org/0000-0001-9652-165X)
- Paweł Kleczyński (ORCID: https://orcid.org/0000-0002-8591-8739)
- Łukasz Rzeszutko (ORCID: https://orcid.org/0000-0001-6352-6024)
- Jacek Legutko (ORCID: https://orcid.org/0000-0002-2945-3674)
- Artur Dziewierz (ORCID: https://orcid.org/0000-0002-2100-5076)
Institutions
- Jagiellonian University (PL)
- John Paul II Hospital (PL)
- Institute of Cardiology (PL)
- Krakow Cardiovascular Research Institute (PL)
Publication Details
- Journal
- Catheterization and Cardiovascular Interventions
- Published
- 2025-11-09
- DOI
- https://doi.org/10.1002/ccd.70303
- Primary Topic
- Cardiac Valve Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00