Distinguishing Between Presbycusis and Noise-Induced Hearing Loss With a Joint-Otoacoustic Emission Profile

In any given ear, DPOAEs and SFOAEs show distinct effects of and sensitivities to hearing loss. Exploiting these fundamental differences may enhance the differential diagnosis of hearing impairment and allow us to distinguish between common etiologies of hearing loss. In this study, the DPOAE at high frequencies was the most effective predictor of etiology. SFOAEs showed a selective sensitivity to NIHL, though their contribution to distinguishing etiology was limited. It is likely that findings were impacted by the relatively small cohort. Application of a Joint-OAE Profile for the differential diagnosis of hearing loss warrants further development with larger groups and varied etiologies. Identifying the dominant etiology in impaired ears could guide targeted intervention and assist in the selection of candidates for genetic and/or pharmaceutical therapies.