Study on the Mechanism of Action of Qi Zhu Formula in the Treatment of Metabolic-associated Fatty Liver Disease based on Network Pharmacologyand Experimental Validation

QZF ameliorates MAFLD by improving serum profiles, inhibiting lipid synthesis (via AMPK activation, suppressing SREBP1C/FASN/ACC1), reducing inflammation, and attenuating liver injury. Its "multi-target-multi-pathway" action supports its potential as a novel MAFLD treatment.

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Publication Details

Journal
Current Computer - Aided Drug Design
Published
2025-11-05
DOI
https://doi.org/10.2174/0115734099394452251014103956
Citations
1
Primary Topic
Liver Disease Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
1.35
Controls
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article

Study on the Mechanism of Action of Qi Zhu Formula in the Treatment of Metabolic-associated Fatty Liver Disease based on Network Pharmacologyand Experimental Validation

Qiuyi Zhang
1 citations
Current Computer - Aided Drug Design
Liver Disease Diagnosis and Treatment
1.35
article

Study on the Mechanism of Action of Qi Zhu Formula in the Treatment of Metabolic-associated Fatty Liver Disease based on Network Pharmacologyand Experimental Validation

Qiuyi Zhang
article en
1 citations

Abstract

QZF ameliorates MAFLD by improving serum profiles, inhibiting lipid synthesis (via AMPK activation, suppressing SREBP1C/FASN/ACC1), reducing inflammation, and attenuating liver injury. Its "multi-target-multi-pathway" action supports its potential as a novel MAFLD treatment.

Current Computer - Aided Drug DesignVol. 22
Shanghai University of Traditional Chinese Medicine (CN), Shuguang Hospital (CN)
Openalex Percentile: Top 14%
Liver Disease Diagnosis and Treatment
1.35
DOISourceOpenAlex
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Study on the Mechanism of Action of Qi Zhu Formula in the Treatment of Metabolic-associated Fatty Liver Disease based on Network Pharmacologyand Experimental Validation — Qiuyi Zhang · Current Computer - Aided Drug Design (2025) | TGRS Research Map | TGRS