Cumulative corticosteroid burden over 25 years in patients initiating biologic therapy for severe asthma: a nationwide cohort study
Patients with severe asthma have substantial cumulative corticosteroid exposure prior to biologic therapy, with the majority occurring prior to specialist assessment. Exposure reduction is a key priority to minimise corticosteroid exposure-related comorbidities.
Authors
- Barbara Bonnesen
- Anna von Bülow (ORCID: https://orcid.org/0009-0005-3268-785X)
- Marianne Baastrup Soendergaard (ORCID: https://orcid.org/0000-0002-4954-0863)
- Ole Hilberg (ORCID: https://orcid.org/0000-0002-3075-3463)
- Susanne Hansen (ORCID: https://orcid.org/0000-0002-9550-6703)
- Sofie Lock Johansson (ORCID: https://orcid.org/0000-0003-0597-9468)
- Charlotte Suppli Ulrik (ORCID: https://orcid.org/0000-0001-8689-3695)
- Kjell Erik Julius Håkansson (ORCID: https://orcid.org/0000-0001-5804-0740)
- Johannes Martin Schmid (ORCID: https://orcid.org/0000-0002-4558-2943)
- Celeste Porsbjerg (ORCID: https://orcid.org/0000-0003-4825-9436)
- Claus Rikard Johnsen (ORCID: https://orcid.org/0009-0008-4149-4592)
- Anne‐Sofie Bjerrum (ORCID: https://orcid.org/0009-0002-1657-2399)
- Linda Makowska Rasmussen
- Galathea Berner (ORCID: https://orcid.org/0009-0006-5569-4240)
Institutions
- Frederiksberg Hospital (DK)
- Odense University Hospital (DK)
- Bispebjerg Hospital (DK)
- Hvidovre Hospital (DK)
- Aarhus University Hospital (DK)
- Copenhagen University Hospital (DK)
- Gentofte Hospital (DK)
- Vejle Sygehus (DK)
Publication Details
- Journal
- ERJ Open Research
- Published
- 2025-11-09
- DOI
- https://doi.org/10.1183/23120541.00677-2025
- Primary Topic
- Asthma and respiratory diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00