Keratin-5-positive basal-like epithelial cells associate with forced vital capacity in idiopathic pulmonary fibrosis; a cross-sectional analysis
<b>Elevated expression of keratin-5-positive basal-like epithelial cells correlates strongly with reduced %FVC, indicating restrictive ventilatory impairment in IPF. KRT5 may serve as a biomarker of disease severity and aberrant epithelial remodelling.</b> https://bit.ly/4oZeTSg.
Authors
- Shinya Ohkouchi (ORCID: https://orcid.org/0000-0002-4658-6487)
- Hájíme Kurosawa (ORCID: https://orcid.org/0000-0003-1793-6852)
- Hisatoshi Sugiura (ORCID: https://orcid.org/0000-0002-4335-7048)
- Yoshinori Okada (ORCID: https://orcid.org/0000-0001-7739-7657)
- Taizou Hirano
- Ryoko Saitou-Koyama
Institutions
- Tohoku Institute of Technology (JP)
- Hirosaki University (JP)
- Tohoku University (JP)
- Sendai Medical Center (JP)
- National Hospital Organization (JP)
Publication Details
- Journal
- ERJ Open Research
- Published
- 2025-11-09
- DOI
- https://doi.org/10.1183/23120541.00742-2025
- Primary Topic
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00