Real-World Outcomes and Subsequent Treatment Patterns in Patients with Advanced Non-Small Cell Lung Cancer and Atypical EGFR Mutations Receiving First-Line Osimertinib Monotherapy
First-line osimertinib may provide real-world clinical benefits for patients with advanced NSCLC with atypical EGFR mutations, with results suggesting greater benefit in those harboring compound EGFR mutations.
Authors
- Deborah B. Doroshow (ORCID: https://orcid.org/0000-0002-2221-9818)
- Leslie Servidio (ORCID: https://orcid.org/0009-0000-3121-8238)
- Yan Kwan Lau (ORCID: https://orcid.org/0000-0002-1612-9912)
- Miranda Cooper
- Pritesh S. Karia (ORCID: https://orcid.org/0000-0001-6440-9452)
- Jorge J. Nieva (ORCID: https://orcid.org/0000-0003-1605-4719)
- Jacqulyne Robichaux (ORCID: https://orcid.org/0000-0001-8812-7054)
- Xuejun Wang (ORCID: https://orcid.org/0000-0002-7034-0460)
Institutions
- AstraZeneca (Netherlands) (NL)
- AstraZeneca (Singapore) (SG)
- AstraZeneca (Brazil) (BR)
- USC Norris Comprehensive Cancer Center (US)
- AstraZeneca (Japan) (JP)
- AstraZeneca (United States) (US)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- Oncology and Therapy
- Published
- 2025-11-09
- DOI
- https://doi.org/10.1007/s40487-025-00395-7
- Primary Topic
- Lung Cancer Treatments and Mutations
- Type
- article
- Field-Weighted Citation Impact
- 0.00