Tubulonodular Pericallosal Lipoma With Callosal Dysgenesis in an Adult Presenting With a Lapse in Consciousness: A Case Report

Intracranial lipomas are rare congenital anomalies that result from the abnormal development of meningeal tissues, causing the formation of fatty deposits within the intracranial cavity. The pericallosal region is the most frequent site where such lipomas are often associated with structural abnormalities of the corpus callosum. Although many cases remain clinically silent, symptomatic presentations can include seizures, headaches, cognitive impairment, or unusual neurobehavioral findings. We present the case of a 30-year-old woman who was evaluated in the emergency department after a motor vehicle accident, which was preceded by a transient loss of consciousness, presumed to be a seizure. Neuroimaging revealed a tubulonodular pericallosal lipoma associated with callosal dysgenesis.

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Publication Details

Journal
Cureus
Published
2025-11-09
DOI
https://doi.org/10.7759/cureus.96431
Primary Topic
Teratomas and Epidermoid Cysts
Type
article
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0.00
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article

Tubulonodular Pericallosal Lipoma With Callosal Dysgenesis in an Adult Presenting With a Lapse in Consciousness: A Case Report

Ayomide O Ayo-Salami, Godknows Osarhiaekhimen, Adeolu Morawo
Cureus
Teratomas and Epidermoid Cysts
article

Tubulonodular Pericallosal Lipoma With Callosal Dysgenesis in an Adult Presenting With a Lapse in Consciousness: A Case Report

Ayomide O Ayo-Salami, Godknows Osarhiaekhimen, Adeolu Morawo
article en

Abstract

Intracranial lipomas are rare congenital anomalies that result from the abnormal development of meningeal tissues, causing the formation of fatty deposits within the intracranial cavity. The pericallosal region is the most frequent site where such lipomas are often associated with structural abnormalities of the corpus callosum. Although many cases remain clinically silent, symptomatic presentations can include seizures, headaches, cognitive impairment, or unusual neurobehavioral findings. We present the case of a 30-year-old woman who was evaluated in the emergency department after a motor vehicle accident, which was preceded by a transient loss of consciousness, presumed to be a seizure. Neuroimaging revealed a tubulonodular pericallosal lipoma associated with callosal dysgenesis.

CureusVol. 17(11)
Creighton University (US), American University of Integrative Sciences (SX), Education Trust (US)
Openalex Percentile: Top 48%
Teratomas and Epidermoid Cysts
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Tubulonodular Pericallosal Lipoma With Callosal Dysgenesis in an Adult Presenting With a Lapse in Consciousness: A Case Report — Ayomide O Ayo-Salami, Godknows Osarhiaekhimen, et al. · Cureus (2025) | TGRS Research Map | TGRS