History of Peyronie’s disease: from early descriptions to modern treatments
A review of the historical progression of PD management demonstrates the shift from anecdotal claims of treatment efficacy to evidence-based practice. Current guidelines recommend ILI and PTT as first-line nonsurgical management, with surgery providing exceptional outcomes. Future progress aims to gain a greater molecular understanding of fibrosis and tissue remodeling to foster targeted therapies.
Authors
- William Fuell
- Alexandre Franco Miranda (ORCID: https://orcid.org/0000-0002-9965-1406)
- Donald T. McKnight (ORCID: https://orcid.org/0000-0001-8543-098X)
- Wayne J.G. Hellstrom (ORCID: https://orcid.org/0000-0003-1284-959X)
- Landon Trost (ORCID: https://orcid.org/0000-0002-6842-733X)
- Bruno Machado (ORCID: https://orcid.org/0000-0003-4653-2267)
- Ronald L. Lewis (ORCID: https://orcid.org/0009-0003-6540-2342)
Institutions
- Brigham Young University (US)
- Tulane University (US)
- Augusta University (US)
- Instituto Federal do Rio de Janeiro (BR)
- Jackson and Tull (United States) (US)
- University of Arkansas for Medical Sciences (US)
Publication Details
- Journal
- Sexual Medicine Reviews
- Published
- 2025-11-09
- DOI
- https://doi.org/10.1093/sxmrev/qeaf064
- Primary Topic
- Sexual function and dysfunction studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Tulane University