Desmoplastic infantile ganglioglioma/astrocytoma: Expanding the molecular and morphological spectrum with a novel BRAF fusion

DIG/DIA is a low-grade tumor seen in early childhood and characterized by an indolent clinical course. The most common molecular signature of these tumors is <i>BRAF</i> alterations, including rearrangements. The primary differential diagnosis is infant-type hemispheric glioma and given the similarities, pathologists must remain careful to ensure accurate diagnosis.

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Publication Details

Journal
Neuro-Oncology Advances
Published
2025-11-09
DOI
https://doi.org/10.1093/noajnl/vdaf224
Primary Topic
Glioma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Desmoplastic infantile ganglioglioma/astrocytoma: Expanding the molecular and morphological spectrum with a novel BRAF fusion

Berrin Babaoğlu, İbrahim Kulaç, Figen Söylemezoğlu, Makbule Aydın
Neuro-Oncology Advances
Glioma Diagnosis and Treatment
article

Desmoplastic infantile ganglioglioma/astrocytoma: Expanding the molecular and morphological spectrum with a novel BRAF fusion

Berrin Babaoğlu, İbrahim Kulaç, Figen Söylemezoğlu, Makbule Aydın
article en

Abstract

DIG/DIA is a low-grade tumor seen in early childhood and characterized by an indolent clinical course. The most common molecular signature of these tumors is <i>BRAF</i> alterations, including rearrangements. The primary differential diagnosis is infant-type hemispheric glioma and given the similarities, pathologists must remain careful to ensure accurate diagnosis.

Neuro-Oncology AdvancesVol. 8(1)
Koç University (TR), Hacettepe University (TR)
Openalex Percentile: Top 54%
Glioma Diagnosis and Treatment
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