Familial Hypercholesterolemia Screening in Childhood and Early Adulthood
Sequential FH screening in childhood or early adulthood could be effective but not cost-effective vs usual care. However, sequential FH screening could become cost-effective under highly optimistic assumptions about increased lifestyle therapy and increased lifetime lipid monitoring for patients with non-FH dyslipidemias.
Authors
- Dhruv S. Kazi (ORCID: https://orcid.org/0000-0002-9510-2979)
- Andrew Edward Moran (ORCID: https://orcid.org/0000-0003-3554-0085)
- Norrina B. Allen (ORCID: https://orcid.org/0000-0002-6993-4384)
- Amit V. Khera (ORCID: https://orcid.org/0000-0001-6535-5839)
- Natalia Ruiz‐Negrón (ORCID: https://orcid.org/0000-0003-1775-8128)
- Brandon Kyle Bellows (ORCID: https://orcid.org/0000-0003-1395-6047)
- Elaine M. Urbina (ORCID: https://orcid.org/0000-0002-5640-6777)
- David R. Jacobs (ORCID: https://orcid.org/0000-0002-7232-0543)
- Sarah D. de Ferranti (ORCID: https://orcid.org/0000-0002-8561-6781)
- Jessica Graus Woo (ORCID: https://orcid.org/0000-0003-3644-8432)
- John B. Wong (ORCID: https://orcid.org/0000-0003-4203-9010)
- Yiyi Zhang (ORCID: https://orcid.org/0000-0002-8663-5001)
Institutions
- Northwestern University (US)
- Brigham and Women's Hospital (US)
- Cincinnati Children's Hospital Medical Center (US)
- Tufts Medical Center (US)
- University of Minnesota (US)
- Harvard University (US)
- Columbia University Irving Medical Center (US)
- St. Cloud Hospital (US)
- Verve Therapeutics (United States) (US)
- Minnesota Department of Health (US)
- Deaconess Hospital (US)
- University of Cincinnati Medical Center (US)
Publication Details
- Journal
- JAMA
- Published
- 2025-11-09
- DOI
- https://doi.org/10.1001/jama.2025.20648
- Citations
- 4
- Primary Topic
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Type
- article
- Field-Weighted Citation Impact
- 5.18