Chronic inflammatory burden on aortic valve disorders and atrioventricular block risk in SpA: an ambispective cohort study
The duration of MSK symptoms more strongly predicted all outcomes than extra-MSK symptoms. Age's impact mirrored general population trends. Surprisingly, hypertension protected against aortic conditions, prompting further research into IL-17 therapies. Peripheral SpA significantly predicted aortic valve sclerosis, and enthesitis strongly predicted AVB.
Authors
- Hye Sang Park (ORCID: https://orcid.org/0000-0002-4972-9527)
- Hèctor Corominas (ORCID: https://orcid.org/0000-0002-7738-6787)
- Jesus Sánchez-Vega
- L. Sainz Comas (ORCID: https://orcid.org/0000-0001-9249-1983)
- A. Laíz (ORCID: https://orcid.org/0000-0002-2820-4801)
- Anna López‐Ferrer (ORCID: https://orcid.org/0000-0002-2121-963X)
- C. Marco Pascual
- A. Casals Urquiza
- Avdulla Alija (ORCID: https://orcid.org/0000-0001-9138-9493)
Institutions
- Hospital de Sant Pau (ES)
- Bellvitge University Hospital (ES)
- Hospital Clínic de Barcelona (ES)
Publication Details
- Journal
- Lara D. Veeken
- Published
- 2025-11-05
- DOI
- https://doi.org/10.1093/rheumatology/keaf560
- Primary Topic
- Cardiac Valve Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00